Characterize skin physiology parameters utilized in dermal physiologically-based pharmacokinetic model development across different skin disease states

Funding Opportunity RFA-FD-18-017 from the NIH Guide for Grants and Contracts. The purpose of this project is to identify skin physiology characteristics that differ between healthy and skin disease population groups and incorporate them into dermal physiologically-based pharmacokinetic models to improve their predictability. The models developed will be utilized to perform virtual bioequivalence assessments between brand name and generic drug products to inform regulatory decisions relating to the development of generic topical dermatological drug products and transdermal delivery systems.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding