An Ovariectomy-Induced Rabbit Osteoporotic Model: A New Perspective.

Conclusions: This study is the first to demonstrate a significant bone loss within four months of pure OVX in rabbits using animal-sparing validation techniques. We believe that this OVX model is safe, reproducible, and can be employed to longitudinally evaluate the effect of anti-osteoporosis therapeutics and surgical interventions. PMID: 29503677 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/29503677?dopt=Abstract

Source: Asian Spine Journal - March 7, 2018 Category: Orthopaedics Tags: Asian Spine J Source Type: research