Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder

Glycans are short chains of saccharides linked to glycoproteins that are known to be involved in a wide range of inflammatory processes. As depression has been consistently associated with chronic low-grade inflammation, we asked whether patients with Major Depressive Disorder show alterations in the N-glycosylation pattern of serum proteins that might be linked to associated changes in inflammatory processes.

Source: Journal of Affective Disorders - February 27, 2018 Category: Neurology Authors: Christina Boeck, Sophia Pfister, Alexander B ürkle, Valerie Vanhooren, Claude Libert, Juan Salinas-Manrique, Detlef E Dietrich, Iris-Tatjana Kolassa, Alexander Karabatsiakis Tags: Research paper Source Type: research