GSE95771 AG221 and Ruxolitinib Treatment Effects on LSKs in IDH2-R140Q JAK2-V617F Transplant Recipients

Contributors : Anna S McKenney ; Barbara Spitzer ; Ross L LevineSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTransplant recipients of IDH2-R140Q JAK2-V617F expressing bone marrow were treated with AG221 and ruxolitinib monotherapy, combined therapy, or vehicle. LSKs were sorted from terminal samples and sequenced with three WT controls.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

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Biolife4D has achieved a milestone in its ultimate quest to develop human organs for transplant. The company recently announced that it has developed a cardiac patch using a highly specialized 3D printer designed to protect living cells during the printing process. The patch is designed to help patients recover heart function after an acute myocardial infarction, said Ravi Birla, PhD, the company’s chief science officer, in an interview with MD+DI. “Over several weeks, acute myocardial infarction results in scar formation and progresses to chronic heart failure, severely damp...
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