GSE95771 AG221 and Ruxolitinib Treatment Effects on LSKs in IDH2-R140Q JAK2-V617F Transplant Recipients

Contributors : Anna S McKenney ; Barbara Spitzer ; Ross L LevineSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTransplant recipients of IDH2-R140Q JAK2-V617F expressing bone marrow were treated with AG221 and ruxolitinib monotherapy, combined therapy, or vehicle. LSKs were sorted from terminal samples and sequenced with three WT controls.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research

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Team of researchers changes microbes in koalas ’ guts in order to improve type of food they consumeScientists believe they have found a new weapon in the battle to save endangered species: faecal transplants. They say that by transferring faeces from the gut of one animal to another they could boost the health and viability of endangered creatures. In particular, they believe the prospects of saving the koala could be boosted this way.The idea of using faecal transplants as conservation weapons was highlighted this month at the American Society for Microbiology meeting in Atlanta, where scientists outlined experiment...
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Authors: Spiliopoulos S, Hergesell V, Wasler A, Dapunt O Abstract Due to the declining instances of organ donation, total artificial heart (TAH) therapy is of increasing importance for the management of end-stage biventricular heart failure. We introduce the currently most important established and novel TAH systems (SynCardia, CARMAT, ReinHeart, BiVACOR), report clinical outcomes and discuss technical requirements for the successful implementation of TAH therapy as an alternative to cardiac transplantation. PMID: 29902152 [PubMed - as supplied by publisher]
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Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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Source: Journal of Biomechanics - Category: Biomedical Science Authors: Source Type: research
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