[Correspondence] Use of prevalence data to study sepsis incidence and mortality in intensive care units – Authors' reply

Sam Doerken and colleagues point out relevant limitations to our observational study1 with the use of conversion formulas to estimate incidence from prevalence data. We agree and have actually pointed out this issue in our list of limitations in the discussion of study.1 However, no reliable estimates of sepsis incidence in intensive care units (ICUs) from cohort studies in Brazil currently exist. Therefore, the figures we provided, 290 (95% CI 237 ·9–351·2) cases of ICU-treated sepsis per 100 000 adult population with approximately 420 000 cases of sepsis per year in Brazil, are intended to be considered as rough estimates of the sepsis incidence in the country.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research