Author Correction: Beta cell connectivity in pancreatic islets: a type 2 diabetes target?

Author Correction: Beta cell connectivity in pancreatic islets: a type 2 diabetes target? Cell Mol Life Sci. 2018 Feb 15;: Authors: Rutter GA, Hodson DJ Abstract The original version of this article unfortunately contained a mistake. Legends of Figures 1 and 2 were interchanged. The correct versions are given below. PMID: 29450573 [PubMed - as supplied by publisher]
Source: Cellular and Molecular Life Sciences : CMLS - Category: Cytology Authors: Tags: Cell Mol Life Sci Source Type: research

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In a society where physical activity is limited and food supply is abundant, metabolic diseases are becoming a serious epidemic. Metabolic syndrome (MetS) represents a cluster of metabolically related symptoms such as obesity, hypertension, dyslipidemia, and carbohydrate intolerance, and significantly increases type 2 diabetes mellitus risk. Insulin resistance and hyperinsulinemia are consistent characteristics of MetS, but which of these features is the initiating insult is still widely debated. Regardless, both of these conditions trigger adverse responses from the pancreatic β cell, which is responsible for produci...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
This study aimed to explore the association between thyroid dysfunction and OSA in the adults with prediabetes or diabetes mellitus type 2, who have very high prevalence of OSA.MethodsOSA was assessed using an in-home monitoring device, WatchPAT200. OSA severity was measured using apnea-hypopnea index (AHI), oxygen desaturation index (ODI), minimum oxygen saturation (minO2), and time spent under oxygen saturation
Source: Sleep and Breathing - Category: Respiratory Medicine Source Type: research
Many patients with type 2 diabetes are overtreated, leading to more than 9000 preventable hospital visits over 2 years, a modeling study found.Medscape Medical News
Source: Medscape Diabetes Headlines - Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news
Condition:   Type 2 Diabetes With Renal Manifestations Interventions:   Drug: Semaglutide, 1.34 mg/mL;   Other: Placebo, 1,34 mg/mL;   Drug: Empagliflozin 25 MG Sponsors:   Steno Diabetes Center Copenhagen;   Novo Nordisk A/S Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsPatients with DM are prone to the early development of CAD, and psychological factors were associated with early development of CAD. Therefore, the findings of the current study can be utilized in designing preventive and therapeutic interventions, and implementing and integrating these factors in health-promotion programs for patients with DM can be useful.
Source: Clinical Epidemiology and Global Health - Category: Epidemiology Source Type: research
TYPE 2 diabetes requires a person to overhaul aspects of their lifestyle to stave off the risk. Fortunately, the disease can be prevented by making certain lifestyle decisions, including eating a popular food group, a study has revealed.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Mesenchymal stem cells (MSCs) have emerged as a promising therapy for type 2 diabetes (T2D). Mechanistic researches demonstrate that the anti-diabetic effect of MSCs is partially mediated by eliciting macropha...
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Research Source Type: research
AbstractImmune checkpoint inhibitors (CPI) are increasingly being used in oncology, and many autoimmune side effects have been described. Diabetes mellitus (DM) has been reported in approximately 1% of subjects treated with programmed cell death-1 and programmed death ligand 1 (PD-1/PD-L1) inhibitors, alone or in association with CTLA-4 inhibitors. In the present mini-review, we aimed to describe different clinical pictures and pathophysiology associated with these forms of diabetes. Data on CPI-related DM was gathered from the largest case series in the literature and from our centre dedicated to immunotherapy complicatio...
Source: Acta Diabetologica - Category: Endocrinology Source Type: research
AbstractBackgroundSleeve gastrectomy (SG) has become the most popular bariatric procedure. Although bariatric surgery is recommended for type 2 diabetes mellitus (T2DM) in Asian patients with BMI 27.5 –32.4 kg/m2, reported evidences, especially following SG, are still lacking.MethodsPatients ’ data from June 2016 to June 2018 that underwent SG as primary surgery at our setting were analyzed. Patients with T2DM, without insulin use and BMI 27.5–30 kg/m2, were our main criteria. Preoperative and postoperative parameters were as such: age, BMI, T2DM duration, anti-diabetic medications, fasting plas...
Source: Obesity Surgery - Category: Surgery Source Type: research
ConclusionsWorkplace interventions show promise for improving cardiometabolic risk markers. The BCTs with the greatest promise of cardiometabolic risk marker improvements included social comparison,  those related to individual habits, and behaviour goals.RegistrationThis systematic review was prospectively registered in PROSPERO (CRD42017072427).
Source: Sports Medicine - Category: Sports Medicine Source Type: research
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