Poly(lactic-co-glycolic) Acid as a Slow-Release Drug-Carrying Matrix for Methotrexate Coated onto Intraocular Lenses to Conquer Posterior Capsule Opacification.

CONCLUSIONS: In view of the strong inhibition of PCO in vitro with the lack of toxic effects on a corneal cell line, MTX encapsulating microspheres seem to be a promising method for modifying IOL.
PMID: 29451997 [PubMed - as supplied by publisher]

Source: Current Eye Research - February 16, 2018 Category: Opthalmology Authors: Kassumeh SA, Wertheimer CM, von Studnitz A, Hillenmayer A, Priglinger C, Wolf A, Mayer WJ, Teupser D, Holdt LM, Priglinger SG, Eibl-Lindner KH Tags: Curr Eye Res Source Type: research