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Parents want children to be labelled autistic

Let me make one thing clear: I do not doubt the existence of ADHD, but today, I believe such conditions are vastly, and dangerously, over-diagnosed, writes DR MIKE SHOOTER.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news

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(BMJ. 2017;358:j3668) Antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), are prescribed during pregnancy and are considered safe. Recent studies have raised concerns regarding the long-term neurodevelopmental effects, such as autism and attention-deficit/hyperactivity disorder, of these medications on the offspring. However, gaps exist in the knowledge of antidepressant use during pregnancy and risk of psychiatric disorders in the offspring. This population-based cohort study was performed to investigate the association between in utero antidepressant exposure and overall risk of psychiatric disorders in children.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports, Surveys Source Type: research
Publication date: Available online 12 May 2018 Source:Pharmacology & Therapeutics Author(s): Samata R. Sharma, Xenia Gonda, Frank I. Tarazi Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not otherwise specified (PDD-NOS). The new diagnostic criteria of ASD focuses on two core domains: social communication impairment and restricted interests/repetitive behaviors. The prevalence of ASD has been steadily increasing over the past two decades, with current estimates reaching up to 1 in 36 children. Hereditary f...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Genetic factors are known to significantly contribute to the etiology of psychiatric diseases such as attention deficit hyperactivity disorder (ADHD) and autism spectrum and bipolar disorders, but the underlying molecular processes remain largely elusive. The dopamine transporter (DAT) has received continuous attention as a potential risk factor for psychiatric disease, as it is critical for dopamine homeostasis and serves as principal target for ADHD medications. Constrain metrics for the DAT-encoding gene, solute carrier family 6 member 3 (SLC6A3), indicate that missense mutations are under strong negative selection, poi...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Molecular Bases of Disease Source Type: research
Abstract De novo variants of ASH1L, which encodes a histone methyltransferase, have been reported in a few patients with intellectual disability and autistic features. Here, we identified a novel de novo frame-shift variant, c.2422_2423delAAinsT which predicts p.(Lys808TyrfsTer40), in ASH1L in a patient with multiple congenital anomalies (MCA), fine motor developmental delay, learning difficulties, attention deficit hyperactivity disorder, sleep apnea, and scoliosis. This frame-shift variant is expected to result in loss-of-function. Our report provides further evidence to support loss-of-function alterations of A...
Source: European Journal of Medical Genetics - Category: Genetics & Stem Cells Authors: Tags: Eur J Med Genet Source Type: research
The objective of this study is to determine the psychometric properties of the Turkish version of the Autism Spectrum Screening Questionnaire (ASSQ-TR) and to find the best cutoff score for Pervasive Developmental Disorder (PDD) cases. METHOD: Children between 6 to 18 years old with diagnoses of PDD, Obsessive Compulsive Disorder (OCD), and Attention Deficit Hyperactivity Disorder (ADHD) were included. The healthy control (HC) group was recruited from children who did not have any psychiatric complaints or history. Furthermore, parents of 268 children filled the ASSQ-TR. Of the children, 51 were PDD, 67 were ADHD, 50 w...
Source: Turk Psikiyatri Dergisi - Category: Psychiatry Tags: Turk Psikiyatri Derg Source Type: research
MRI scans appear to have uncovered abnormalities in certain brain pathways...Read more on AuntMinnie.comRelated Reading: MRI shows smaller brain volume in kids with ADHD Machine learning predicts working-memory performance MRI, radiomics help diagnose, discern ADHD subtypes DTI shows how music could help kids with autism, ADHD 3D MRI shows risks in premature infants
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Abstract Relatively limited research has been devoted to understanding the postsecondary experience from the students' perspectives. In the current study, individual interviews were conducted with university students with autism spectrum disorder (n = 13) and students with Attention Deficit/Hyperactivity Disorder (n = 18) to investigate likely factors impeding meaningful postsecondary experiences. Through an iterative coding process, nine themes were identified, and direct narratives exemplifying each are included. Overall, both diagnostic groups reported significant social, emotional, ...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
AbstractMany genetic causes of developmental delay and/or intellectual disability (DD/ID) are extremely rare, and robust discovery of these requires both large-scale DNA sequencing and data sharing. Here we describe a GeneMatcher collaboration which led to a cohort of 13 affected individuals harboring protein-altering variants, 11 of which are de novo, inMED13; the only inherited variant was transmitted to an affected child from an affected mother. All patients had intellectual disability and/or developmental delays, including speech delays or disorders. Other features that were reported in two or more patients include aut...
Source: Human Genetics - Category: Genetics & Stem Cells Source Type: research
Developmental Science, EarlyView.
Source: Developmental Science - Category: Child Development Authors: Source Type: research
Conclusion: While the integrated, per capita, exposure of PM for a large fraction of the first-world may be less than 1 mg per day, links between several syndromes, including attention deficit hyperactivity disorder (ADHD), autism, loss of cognitive function, anxiety, asthma, chronic obstructive pulmonary disease (COPD), hypertension, stroke, and PM exposure have been suggested. This article reviews and summarizes such links reported in the literature.
Source: Journal of Occupational and Environmental Medicine - Category: Occupational Health Tags: Original Articles Source Type: research
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