Reduction of SPECT MPI Radiation Dose Using Contemporary Protocols and Technology
ConclusionsSeveral NPs can be engineered to achieve suitable chemistry, physical properties, and morphology, overcoming many limitations of other conventional approaches. By modifying their size, it is possible to increase or decrease their biological half-life and maximize uptake in tumors due to the enhanced permeability and retention effect. It is also possible to bind to their surface different ligands like monoclonal antibodies or peptides to increase their specificity for tumor antigens.
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) will host a special...Read more on AuntMinnie.comRelated Reading: SNMMI offers open access option for JNM SNMMI seeks to boost molecular imaging's value SNMMI asks Aetna to reconsider PET tracer policy SNMMI offers patient video on DaT SPECT exams SNMMI urges CMS to classify radiotracers as drugs
Whether myocardial ischemia identified using myocardial perfusion imaging (MPI) can be an alternative target of coronary revascularization to reduce the incidence of cardiac events remains unclear.
Chem. Commun., 2018, Advance Article DOI: 10.1039/C8CC03407A, CommunicationKyangwi P. Malikidogo, Isidro Da Silva, Jean-Francois Morfin, Sara Lacerda, Laurent Barantin, Thierry Sauvage, Julien Sobilo, Stephanie Lerondel, Eva Toth, Celia S. Bonnet Quantitative zinc determination by nuclear and MR imaging using two Ln3+ complexes, including purified165Er3+, indispensable for metal ion quantification. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Authors: Kurihara M, Sasaki T, Ishiura H, Tsuji S Abstract Cardiac 123I-metaiodobenzylguanidine (MIBG) scintigraphy is a promising biomarker for dementia with Lewy bodies (DLB). However, we experienced a patient with cognitive decline, parkinsonism, and a decreased MIBG uptake who turned out to have HIV dementia. Normal dopamine transporter single-photon emission computed tomography reduced the possibility of comorbid Lewy body pathology causing the patient' s parkinsonism. The decreased MIBG uptake was most likely due to postganglionic sympathetic nerve denervation, which can also be caused by HIV. This case furth...
Publication date: 1 August 2018 Source:Life Sciences, Volume 206 Author(s): Christiano R.R. Alves, Daniele de P. Faria, Camila de G. Carneiro, Alexandre T. Garcez, Vanessa P. Gutierrez, Willian das Neves, Ney R. de Almeida, Yara Cury, Roger Chammas, Patricia C. Brum Noninvasive imaging using positron emission tomography/computed tomography (PET/CT) and single photon emission computed tomography/computed tomography (SPECT/CT) are considered revolutionized approaches to detect bone cancer. Both PET/CT and SPECT/CT technologies have advanced to permit miniaturization, which has provided the advantage of including animals as ...
, Bonnet CS Abstract We propose quantitative assessment of zinc by combining nuclear and MR imaging. We use a cocktail of a Gd3+-complex providing a Zn2+-dependent MRI response and its 165Er3+ analogue allowing for concentration assessment. 165Er is readily obtained in a cyclotron and purified, which is indispensable for successful quantification of metal ions. PMID: 29789839 [PubMed - as supplied by publisher]
The Society of Nuclear Medicine and Molecular Imaging (SNMMI) has made available...Read more on AuntMinnie.comRelated Reading: SNMMI seeks to boost molecular imaging's value SNMMI asks Aetna to reconsider PET tracer policy SNMMI offers patient video on DaT SPECT exams SNMMI urges CMS to classify radiotracers as drugs SNMMI, ASNC offer guidelines for myocardial perfusion imaging with PET
ConclusionsIn this patient with dystonia-deafness syndrome caused byACTB p.Arg183Trp heterozygosity, unprecedented brain imaging findings strongly indicate striatal neuronal/dopaminergic dysfunction as the underlying cause of the dystonia. Pallidal stimulation provided a substantial improvement of the severe generalized dystonia, which is largely sustained at 4-year follow-up, and we advise this treatment to be considered in such patients. We hypothesize that the pleiotropic manifestations of the dystonia-deafness syndrome caused by this mutation derive from diverse developmental functions of beta-actin in neural crest mig...