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Reduction of SPECT MPI Radiation Dose Using Contemporary Protocols and Technology

Source: Journal of the American College of Cardiology: Cardiovascular Imaging - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research

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Over the past several decades, dramatic advances in the diagnosis and treatment of a broad spectrum of diseases and conditions have been made in no small part thanks to the development and advancement of sophisticated technologies, including rapid gene sequencing, active implanted devices, and diagnostic imaging technologies, including but not limited to MR, CT, ultrasound, PET, and single-photon emission computed tomography. However, one of the most ubiquitous, cost-effective, and widely used diagnostic tools is and continues to be physical touch (ie, palpation).
Source: Journal of the American College of Radiology : JACR - Category: Radiology Authors: Tags: The medical physics consult Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
In this study, we evaluated our quantitative method by comparing it with visual analysis using 99mTc-tetrofosmin (TF) stress-rest single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) as the reference standard. Materials and Methods: Forty-three patients who had a significant stenosis on cardiac rest DECT and had received 99mTc-TF stress-rest SPECT MPI within 1 month were retrospectively analyzed. The regions of interest were set on iodine images in accordance with the American Heart Association (AHA) 17-segment model (a total of 731 segments). The regions of interest values were divided ...
Source: Journal of Thoracic Imaging - Category: Radiology Tags: Original Articles Source Type: research
One type of biocompatible nanoparticles functionalized with folate and 99mTc was successfully synthesized. Maleimide‐folic acid (Mal‐FA) was selected to covalently conjugate with ‐SH of the nanoparticles (NPs) to prepare NPs‐FA for targeting. 99mTc was selected to conjugate with ‐NH2 and ‐SH groups of cysteine residues on the surface of NPs to prepare NPs‐FA‐99mTc for radioactive counting. The ability to target folate receptors of NPs‐FA‐99mTc was assessed in uptake studies with folate‐receptor–positive human HepG2 cells. The results showed that the as‐prepared NPs can selectively uptake by fo...
Source: Journal of Labelled Compounds and Radiopharmaceuticals - Category: Biochemistry Authors: Tags: RESEARCH ARTICLE Source Type: research
(a,b) Non‐enhanced magnetic resonance imaging and (c) technetium‐99 m dimercaptosuccinic acid (99mTc‐DMSA) renal scintigraphy, acquired on (a,b) day 6 and (c) day 5 in a 4‐month‐old boy, showing a focal renal lesion and a focal cortical defect. (a) Axial diffuse weighted imaging (DWI) showing a high‐intensity focal lesion (arrow) located on the medial part of the lower pole of the left kidney (top, frontal region; right, left kidney). (b) The same region in (a) showing a low‐intensity signal on the apparent diffusion coefficient (ADC) map (arrow). (c) Coronal single‐photon emission computed tomography (SPEC...
Source: Pediatrics International - Category: Pediatrics Tags: Issue Information Source Type: research
BACKGROUND: Iodine 123 (I-123) iomazenil is a specific ligand of the central benzodiazepine receptor (BZR), which is a part of the postsynaptic γ-aminobutyric acid (GABA) A receptor complex. We performed statistical image processing of I-123 iomazenil single-photon emission computed tomography (SPECT) to elucidate maturational changes in the GABAergic system. METHODS: Thirty patients (18 boys and 12 girls, aged 17 days to 14 years) with cr yptogenic focal epilepsy were enrolled and underwent I-123 iomazenil SPECT.
Source: Pediatric Neurology - Category: Neurology Authors: Tags: Original Article Source Type: research
German industrial conglomerate Siemens AG said this week that its Siemens Healthineers...Read more on AuntMinnie.comRelated Reading: Siemens receives FDA nod for GoKnee3D Siemens to sell Symbia Intevo Bold SPECT/CT in Canada Lower revenue plagues Siemens Healthineers' Q1 numbers Siemens teams up with Florida Hospital Siemens Healthineers plans cost cuts to prepare for IPO
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Excessive daytime sleepiness (EDS) is one of the earliest and most common non-motor symptoms of PD, substantially impacting on patient's quality of life. Using the Parkinson's Progression Markers Initiative database, we performed a case-control study to investigate whether dopaminergic deficit is associated with the development of EDS using dopaminergic specific single photon emission computed tomography (SPECT) molecular imaging of dopamine transporters (DAT). We enrolled 84 early de novo PD patients with EDS and 84 without EDS, who were matched for age, gender, age of diagnosis, years of education and disease duration.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Source Type: research
Siemens Healthineers has received U.S. Food and Drug Administration (FDA) clearance...Read more on AuntMinnie.comRelated Reading: Siemens to sell Symbia Intevo Bold SPECT/CT in Canada Lower revenue plagues Siemens Healthineers' Q1 numbers Siemens teams up with Florida Hospital Siemens Healthineers plans cost cuts to prepare for IPO Report: Siemens targets health IPO for March
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Nuclear medicine imaging of neuroendocrine tumours is performed either by SPECT/CT imaging, using 111In-octreotide or by PET/CT imaging using 68Ga-radiolabelled somatostatin analogs. These imaging techniques will...
Source: EJNMMI Physics - Category: Radiology Authors: Tags: Original research Source Type: research
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