68Ga-NOTA-Functionalized Ubiquicidin: Cytotoxicity, Biodistribution, Radiation Dosimetry, and First-in-Human PET/CT Imaging of Infections

Conclusion: 68Ga-NOTA-UBI is considered a nontoxic, safe-to-administer radiopharmaceutical unlikely to cause adverse effects in humans. The favorable tracer biodistribution and the first-in-human results will make 68Ga-NOTA-UBI PET/CT an encouraging future diagnostic technique with auxiliary clinical relevance.

Source: Journal of Nuclear Medicine - February 1, 2018 Category: Nuclear Medicine Authors: Ebenhan, T., Sathekge, M. M., Lengana, T., Koole, M., Gheysens, O., Govender, T., Zeevaart, J. R. Tags: Basic Source Type: research