Immunotherapy: Oncolytic virotherapy enables checkpoint blockade

Nature Reviews Drug Discovery 17, 96 (2018). doi:10.1038/nrd.2018.11 Author: Sarah Crunkhorn Immune checkpoint inhibitors have yielded promising results in various cancer types, but are only effective in a subset of cancer patients, particularly those exhibiting pre-existing anticancer immunity. Two new papers now report the use of an oncolytic virus (OV) to induce antitumour immunity and increase
Source: Nature Reviews Drug Discovery - Category: Drugs & Pharmacology Authors: Tags: Research Highlight Source Type: research