Inhibitors of the integrase –transportin-SR2 interaction block HIV nuclear import

Combination antiretroviral therapy efficiently suppresses HIV replication in infected patients, transforming HIV/AIDS into a chronic disease. Viral resistance does develop however, especially under suboptimal ...

Source: Retrovirology - January 12, 2018 Category: Virology Authors: Jonas Demeulemeester, Jolien Blokken, St éphanie De Houwer, Lieve Dirix, Hugo Klaassen, Arnaud Marchand, Patrick Chaltin, Frauke Christ and Zeger Debyser Tags: Research Source Type: research