Significance of hepatoprotective liver specific targeted drug delivery: A review on novel herbal and formulation approaches in management of hepatotoxicity.

CONCLUSION: All over the world millions of people are affected by serious liver disorders which are very difficult to treat despite of many efforts. Hepatotoxicity is one of the major reasons behind drugs continue to be taken off from the market. This review highlights the potential of various phytochemicals as hepatoprotective agent and various strategies which have been proposed to achieve liver targeting, includes passive accumulation of therapeutic drug delivery system and active targeting by surface modifications of particulate formulation with specific ligands. PMID: 29299986 [PubMed - as supplied by publisher]
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research