Oxygen Concentration Curves

BSCC Physiology 014 Question: Please draw the curve demonstrating the relationship between oxygen concentration and the partial pressure of Oxygen. - Demonstrate how this changes in polycythaemic and anaemic individuals - Explain what happens to a normal patient when 1/3 of the Haemoglobin is bound to carbon monoxide? Examinee response + Show: Drawing and explanation in real-time video/audio expand(document.getElementById('ddet1002587779'));expand(document.getElementById('ddetlink1002587779')) Examiner explanation: + Show: Drawing and explanation in real-time video/audio expand(document.getElementById('ddet636233393'));expand(document.getElementById('ddetlink636233393')) + Show Transcript expand(document.getElementById('ddet1796978859'));expand(document.getElementById('ddetlink1796978859')) Oxygen Concentration Curves Oxygen is carried in the blood (in two ways): bound to Hb or dissolved 0.3 ml of oxygen is dissolved in every 100ml of blood When bound to Hb 1 gm of HB binds 1.39ml O2 A patient with a normal range of Hb e.g. 15 (15g/100ml blood), the Hb will carry 20.8 ml O2 /100ml blood. (15 X 1.39=20.8) Plotted on the Hb-O2 curve you can see 20ml of oxygen. Notice that at a PaO2 of 90mmhg the range is >95%. A patient who is polycythaemic might have a Hb of 20. This Hb will carry 27.8 ml of O2/100ml of blood. Note: that the concentration of oxygen per 100ml of blood is greater in the polycythaemic patient, but the partial pressure of oxygen and the HB O2 sa...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Basic Science Physiology anaemia Oxygen Concentration Curve polycythaemia Source Type: blogs