Online Resources About Kidney Transplant Too Complex Online Resources About Kidney Transplant Too Complex
Online health education materials about transplant options are far too complex for chronic kidney disease patients to make sense of, U.S. researchers say, and that may prevent this group from deciding on the best treatment.Reuters Health Information
In conclusion, hemin may have a dual effect on renal IRI, protective or deleterious, depending on the timing of its administration. PMID: 30100067 [PubMed - as supplied by publisher]
Liver Transplantation,Volume 0, Issue ja, -Not available-.
Conclusions: The survey results reveal a lack of consensus among providers caring for patients with advanced CKD about the management of ASCVD in this setting. Future randomized controlled trials will be needed to better inform the clinical management of ASCVD in these patients. The limitations of the study include its small sample size and the relatively low response rate among the respondents.Cardiorenal Med 2018;8:285 –295
CONCLUSIONS: The benefits on glucose metabolism and renal function after a sustained viral response in liver transplant recipients appear to be limited to those with early chronic kidney disease and those treated soon after transplant. The potential benefits from direct-acting antiviral agents on these parameters may be overshadowed by the effects of immunosuppressant therapy. PMID: 30060729 [PubMed - in process]
Chronic kidney disease (CKD) currently affects approximately 15% of the US population or 30 million US adults,1 but incidence is projected to increase over the next 2 decades due to the ongoing obesity epidemic and the aging of the US population.2 Almost half of all US adults aged 65 years and older are predicted to develop CKD during their lifetime.2 The economic impact of CKD is substantial. Despite the fact that end-stage renal disease (ESRD), the most severe stage of CKD requiring kidney transplant or dialysis, is experienced only 650,000 US persons, the Medicare costs alone exceed $33 billion annually.
Kidney transplantation (KTx) is the best therapeutic approach for chronic kidney diseases leading to irreversible kidney failure. Considering the origin of the graft, several studies have reported differences ...
Authors: Siemens TA, Riella MC, Moraes TP, Riella CV Abstract There are striking differences in chronic kidney disease between Caucasians and African descendants. It was widely accepted that this occurred due to socioeconomic factors, but recent studies show that apolipoprotein L-1 (APOL1) gene variants are strongly associated with focal segmental glomerulosclerosis, HIV-associated nephropathy, hypertensive nephrosclerosis, and lupus nephritis in the African American population. These variants made their way to South America trough intercontinental slave traffic and conferred an evolutionary advantage to the carrie...
ConclusionsEvaluation of renal anatomy with ultrasound imaging is important at diagnostic workup of FA. While CKD is uncommon at diagnosis, our data suggests that the incidence of CKD increases with age, in particular after haematopoietic stem cell transplantation. Monitoring of renal function is essential for management of FA. Based on these long-term clinical observations, we formulate some practical guidelines for assessment and management of renal abnormalities in FA.
No abstract available
We present a series of cases of presumed de novo collapsing FSGS in 5 transplanted kidneys from 3 deceased donors later identified as carrying 2 APOL1 risk alleles, including 2 recipients from the same donor whose kidneys were transplanted in 2 different institutions. Four of these recipients had viremia in the period preceding the diagnosis of collapsing FSGS. Cytomegalovirus and BK virus infection were present in 3 and 1 of our 5 cases, respectively, around the time that collapsing FSGS occurred. We discuss viral infections, including active cytomegalovirus infection, as possible “second hits” that may lead t...