Tetramethylpyrazine nitrone activates the BDNF/Akt/CREB pathway to promote post ‐ischaemic neuroregeneration and recovery of neurological functions in rats

Conclusion and ImplicationsAs TBN can simultaneously provide neuroprotection and pro‐neurogenic effects, it may be a promising treatment for both acute phase neuroprotection and long‐term functional recovery after ischaemic stroke.

Source: British Journal of Pharmacology - December 22, 2017 Category: Drugs & Pharmacology Authors: Gaoxiao Zhang, Tao Zhang, Ning Li, Liangmiao Wu, Jianbo Gu, Cuimei Li, Chen Zhao, Wei Liu, Luchen Shan, Pei Yu, Xifei Yang, Yaohui Tang, Guo ‐Yuan Yang, Yuqiang Wang, Yewei Sun, Zaijun Zhang Tags: RESEARCH PAPER Source Type: research