Acute myeloid leukemia xenograft success prediction: saving time

• Extracellular,phenotype, apoptosis or cell cycle profile at thawing cannot predict AML xenograft potential.• Leukemic-LTC-Initiating Cells content distinguish fast or delayed engraftment potential.• Here we define a 1-week CFSE-based assay which predict AML xenograft success.

Source: Experimental Hematology - December 15, 2017 Category: Hematology Authors: Emmanuel Griessinger, Jacques Vargaftig, Stuart Horswell, David C. Taussig, John Gribben, Dominique Bonnet Tags: Brief Communications Source Type: research