High-Intensity Exercise May Cut Parkinson's Motor Symptoms High-Intensity Exercise May Cut Parkinson's Motor Symptoms
Patients with de novo Parkinson's disease receiving high-intensity treadmill training had lower 6-month motor symptom scores than those receiving usual care, new research shows.Medscape Medical News
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.7b04641
ConclusionsUrinary dysfunctions in PSP patients were as extensive as those with MSA, and were more severe than those with IPD, especially in the voiding phase. This may reflect the extensive degenerative process of neural structure in PSP patients.
This review discusses the benefits and risks to be considered in selection of deep brain stimulation of the subthalamic nucleus or globus pallidus interna in patients with Parkinson disease.
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The objective of this study was to explore the ability to synchronize activity in a motor network using transcranial magnetic stimulation and to relate this to timing of motor performance. Methods: We examined synchronization in oscillatory activity of cortical motor areas in response to an external input produced by a pulse of transcranial magnetic stimulation. We combined this with EEG to compare the response of 16 presymptomatic Huntington's disease participants with 16 age‐matched healthy volunteers to test whether the strength of synchronization relates to the variability of motor performance at the following 2 task...
Conclusions: The prevalence of PD with and without dementia increases with age and is higher in men than women. We project that the number of persons with PD in the United States will increase substantially by 2060. © 2018 International Parkinson and Movement Disorder Society
Stefan Kammermeier, Lucia Dietrich, Kathrin Maierbeck, Annika Plate, Stefan Lorenzl, Arun Singh, Ahmad Ahmadi, Kai B ötzel
Preterm birth is a prevalent cause of neonatal deaths worldwide. Inflammation has been implicated in spontaneous preterm birth involved in the processes of uterine contractility and membrane rupture. Parkinson protein 7 (PARK7) has been found to play an inflammatory role in non-gestational tissues. The aims of this study were to determine the expression of PARK7 in myometrium and fetal membranes with respect to term labour onset and to elucidate the effect of PARK7 silencing in primary myometrium and amnion cells on pro-inflammatory and pro-labour mediators. PARK7 mRNA expression was higher in term myometrium and fetal mem...