N-acetylcysteine supplementation increases exercise performance and reduces oxidative stress only in individuals with low levels of glutathione.

In conclusion, individuals with low glutathione levels were linked with decreased physical performance, increased oxidative stress and impaired redox metabolism of erythrocytes. NAC supplementation restored both performance and redox homeostasis.
PMID: 29233792 [PubMed - as supplied by publisher]

Source: Free Radical Biology and Medicine - December 9, 2017 Category: Biology Authors: Paschalis V, Theodorou AA, Margaritelis NV, Kyparos A, Nikolaidis MG Tags: Free Radic Biol Med Source Type: research