Insights into the candidacidal mechanism of Ctn[15-34] - a carboxyl-terminal, crotalicidin-derived peptide related to cathelicidins.

CONCLUSION: Overall, Ctn[15-34] displays a synergistic antifungal activity with AMB, an effect that can be further developed into a multi-target therapeutic option with other antimycotics currently in use.
PMID: 29214974 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - December 7, 2017 Category: Microbiology Authors: Cavalcante CSP, de Aguiar FLL, Fontenelle ROS, de Menezes RRPPB, Martins AMC, Falcão CB, Andreu D, Rádis-Baptista G Tags: J Med Microbiol Source Type: research