An Intramolecular Tryptophan-Condensation Approach for Peptide Stapling

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02667F, CommunicationYen Li Eunice Hui, Bhimsen Rout, Yaw Sing Tan, Chandra Verma, Kok-Ping Chan, Charles W. Johannes Stapled peptides are gaining tremendous interest as next-generation therapeutic agents to target protein-protein interactions. Herein, we report an intramolecular peptide stapling method which links two tryptophan residues at C2 position... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research