The utility of contrast-enhanced hypodense sign for the diagnosis of pulmonary invasive mold disease in patients with haematological malignancies.

CONCLUSION: The high specificity of the HyS strongly supports the diagnosis of pulmonary IMD in neutropenic patients, and is highly suggestive breakthrough fungal disease in patients on mould-active antifungal prophylaxis. Advances in knowledge: This is the first systematic analysis of the hypodense sign on contrastenhanced CT; the sign can support the diagnosis of invasive mould disease when other CT signs are uncertain. PMID: 29212355 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29212355?dopt=Abstract

Source: The British Journal of Radiology - December 7, 2017 Category: Radiology Authors: Sassi C, Stanzani M, Lewis RE, Facchini G, Bazzocchi A, Cavo M, Battista G Tags: Br J Radiol Source Type: research