Gum infections tied to increased risk of stomach cancer precursor

(Reuters Health) - Gum infections may increase people ’s risk for sores in the digestive tract that can lead to stomach cancer, a small study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

Related Links:

CONCLUSION: Robot-assisted gastrectomy is a valuable procedure for gastric cancer patients. Beside its feasibility and safety, it reveals an acceptable long-term clinical outcome. PMID: 30416664 [PubMed]
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Authors: He Z, Wang X, Huang C, Gao Y, Yang C, Zeng P, Chen Z Abstract To explore the effect of fetal-lethal non-coding developmental regulatory RNA (FENDRR) in the initiation and progression of gastric cancer (GC). We detected the levels of FENDRR, microRNA-214-3p (miR-214-3p), and ten-eleven-translocation (TET2) in GC tissues and GC cell lines. In addition, we evaluated the location of FENDRR in GC cell lines by fluorescence in situ hybridization (FISH). Cell proliferation and apoptosis were measured by CCK-8 and Hoechst staining assays. Methylation-specific PCR assay (MSP) was used to evaluate the methylation st...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
Conclusion: The assessment of demarcation of EGC using M-NBI was excellent in well-differentiated (WD) adenocarcinoma and lesions below 20 mm in size. However, histopathological confirmation is needed to assess the demarcation of non-WD adenocarcinomas and EGC over 20 mm in size.Digestion
Source: Digestion - Category: Gastroenterology Source Type: research
Conclusion: Collectively, our data indicated that PepE may represent a promising therapeutic lead compound for intervention in gastric cancer metastasis and may also exhibit potential as a DNA methylation inhibitor for use in epigenetic cancer therapy.Cell Physiol Biochem 2018;50:2341 –2364
Source: Cellular Physiology and Biochemistry - Category: Cytology Source Type: research
ConclusionsAutoantibodies against an optimized TAA panel as serum biomarkers appear to help identify the present of early stage EJA.
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
AbstractBackgroundTo compare the efficacy of oxaliplatin-based and oxaliplatin-free adjuvant chemotherapies in patients with different Lauren type gastric cancers after D2 gastrectomy.MethodsFrom our established gastric cancer database, patients with pathological stage II and III gastric cancer who received adjuvant chemotherapy after D2 gastrectomy at Zhongshan Hospital of Fudan University were analyzed. Patients who received different adjuvant chemotherapy regimens were divided into two subgroups: oxaliplatin-based and oxaliplatin-free subgroup. Clinical outcomes were analyzed according to pathological stage and differen...
Source: Gastric Cancer - Category: Gastroenterology Source Type: research
Abstract Staging laparoscopy (SL) is used to assess for radiographically occult metastatic disease and local resectability in selected patients with gastrointestinal malignancies. SL may avoid nontherapeutic laparotomy in patients with unresectable cancer and is associated with shorter length of hospital stay and time to receipt of systemic therapy compared with nontherapeutic laparotomy. With improvements in preoperative imaging, careful patient selection for SL is imperative. SL and peritoneal washings should be considered for patients with distal gastroesophageal and locally advanced gastric cancer before plann...
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: Surg Oncol Clin N Am Source Type: research
Abstract Introduction of the fiberoptic light-source and CCD chip camera resulted in the rapid growth of minimally invasive surgical procedures. In surgical oncology, the change came slowly owing to concerns about adhering to oncological principals while learning to use new technology. Pioneers in minimally invasive colorectal surgery proved that minimally invasive resection for cancer was oncologically noninferior to traditional surgery. Early adopters treating esophageal and gastric cancer established that a minimally invasive approach was feasible with lower morbidity and equivalent oncologic outcomes. These re...
Source: Clinical Colorectal Cancer - Category: Cancer & Oncology Authors: Tags: Surg Oncol Clin N Am Source Type: research
AbstractBackground.Gastroesophageal cancers are often grouped together even though cancers that originate in the esophagus often exhibit different histological features, geographical distribution, risk factors, and clinical characteristics than those originating in the stomach. Herein, we aimed to compare the molecular characteristics of three different gastroesophageal cancer types: esophageal squamous cell carcinoma (ESCC), esophageal adenocarcinoma (EAC), and gastric adenocarcinoma (GAC).Subjects, Materials, and Methods.In total, 3,342 gastroesophageal cancers were examined. Next‐generation sequencing was performed on...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Precision Medicine, Gastrointestinal Cancer Source Type: research
Authors: Yang M, Chen J, Xu L, Shi X, Zhou X, An R, Wang X Abstract Ban-Xia-Xie-Xin-Tang (BXXXT) is a classical formula from Shang-Han-Lun which is one of the earliest books of TCM clinical practice. In this work, we investigated the therapeutic mechanisms of BXXXT for the treatment of multiple diseases using a network pharmacology approach. Here three BXXXT representative diseases (colitis, diabetes mellitus, and gastric cancer) were discussed, and we focus on in silico methods that integrate drug-likeness screening, target prioritizing, and multilayer network extending. A total of 140 core targets and 72 represen...
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
More News: Cancer | Cancer & Oncology | Gastric (Stomach) Cancer | Health | Study