Pre-plan technique feasibility in multi-interstitial/endocavitary perineal gynecological brachytherapy.

Conclusions: We describe a virtual pre-planning technique using a multi-interstitial and endocavitary perineal template. It is based on a virtual work with MRI images. This procedure has shown to be feasible and efficient in clinical practice by facilitating the work of specialists, and reducing uncertainties of the application. PMID: 29204168 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research

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Conclusions: A combination of MRI and CT is a safe alternative approach for cervical cancer HDR brachytherapy. The technique provides comparable dosimetric outcomes to MRI-based planning, while being more cost-effective. PMID: 30479618 [PubMed]
Source: Journal of Contemporary Brachytherapy - Category: Cancer & Oncology Tags: J Contemp Brachytherapy Source Type: research
Conclusion: This is the first report of a CPC marker injected into tumors of the cervix. It can be visualized on CBCT and MRI with reductions in marker loss and artifacts.
Source: In Vivo - Category: Research Authors: Tags: Clinical Studies Source Type: research
CONCLUSION: In current clinical practice, tailored treatments are delivered, and seems to give correct therapeutic index. However, clinical trials are needed to standardise treatment according to patient characteristics and recurrence risk factors. PMID: 30348607 [PubMed - as supplied by publisher]
Source: Cancer Radiotherapie - Category: Cancer & Oncology Authors: Tags: Cancer Radiother Source Type: research
Over the last two decades, magnetic resonance imaging (MRI), with its excellent soft tissue-contrast, has been increasingly used for cancer staging, radiotherapy target delineation, treatment planning and treatment response monitoring. In the late 1990s MR image-guided adaptive brachytherapy (IGABT) was pioneered in cervix cancer [1 –4] and recommendations by the Groupe Européen de Curiethérapie and the European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) introduced MRI-based target concepts and 3D dose–volume evaluation and reporting [5,6].
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original article Source Type: research
The reference standard treatment for cervical cancer is concurrent chemoradiotherapy followed by magnetic resonance imaging (MRI)-guided brachytherapy. Improvements in brachytherapy have increased local control rates, but late toxicity remains high with rates of 11% grade ≥3. The primary clinical target volume (CTV) for external-beam radiotherapy includes the cervix and uterus, which can show significant inter-fraction motion. This means that generous margins are required to cover the primary CTV, increasing the radiation dose to organs at risk and, therefore, toxi city.
Source: Clinical Oncology - Category: Radiology Authors: Source Type: research
Objectives American Brachytherapy Society (ABS)-recommended interstitial brachytherapy (IBT) should be considered for bulky vaginal tumor thicker than 5 mm. The aim of this study was to evaluate the ABS consensus guideline for patients with severe vaginal invasion based on our long-term follow-up results. Methods/Materials The study included 7 patients with vaginal cancer and 14 patients with cervical cancer invading to the lower vagina. Based on prebrachytherapy magnetic resonance imaging findings, patients received intracavitary brachytherapy (ICT) for vaginal tumors 5 mm or less or IBT for vaginal tumors less than ...
Source: International Journal of Gynecological Cancer - Category: Cancer & Oncology Tags: Radiation Therapy Source Type: research
Conclusion MRI-directed BCT is commonly used for cervical cancer patients. Based on our investigation of four independent studies, MRI showed better prediction of positive results than negative results in patients with cervical cancer after BCT. However, more data on the greater numbers of patients are needed to establish the accuracy of MRI detection of cervical cancer after BCT. PMID: 30149749 [PubMed - as supplied by publisher]
Source: Acta Radiologica - Category: Radiology Authors: Tags: Acta Radiol Source Type: research
To identify if baseline patient or magnetic resonance imaging (MRI) features can predict which women are at risk for inadequate tumor coverage with only intracavitary tandem and ovoid (T  + O) brachytherapy and to correlate tumor coverage with clinical outcomes.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
The application of magnetic resonance imaging (MRI) in image-guided brachytherapy has expanded rapidly over the past two decades. In cervix cancer, significant improvements in overall survival, local control and long-term morbidity have been shown in patients treated with MRI-guided brachytherapy, changing clinical practice and directing an international approach to standardise the technique; unifying adaptive target volume definition and dose reporting. MRI-guided prostate brachytherapy has significantly improved the accuracy of tumour and organ-at-risk delineation, facilitating targeted implantation and dose optimisation.
Source: Clinical Oncology - Category: Radiology Authors: Source Type: research
To evaluate the optimal concentration of an Magnetic Resonance Imaging (MRI) marker agent used for Vienna applicator reconstruction in MRI-guided High-Dose-Rate brachytherapy (HDR-BT) for cervical cancer.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
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