Advancement Flap Technique for Anal Fistula in Patients With Crohn's Disease: A Systematic Review of the Literature

Conclusion The review concludes that the advancement flap technique to treat anal fistulas in patients with Crohn's disease is an adequate alternative. New studies are necessary to provide higher-level evidence.
Source: Cirugia Espanola - Category: Surgery Source Type: research

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AbstractExperimental evidence “proves” that IL‐17 plays a critical role in the pathogenesis of inflammatory bowel disease, but blocking IL‐17 makes Crohn's disease worse.[1, 2] Only a subset of patients with melanoma benefit from checkpoint inhibitors[3] and only a subset of patients with any rheumatic disease benefit fr om a specific therapy. A scientist at the NIH using a rodent model can't replicate the experimental results of a scientist at Harvard. The intestinal microbiome might provide the explanation for each of these seemingly disparate conundrums.
Source: Arthritis and Rheumatology - Category: Rheumatology Authors: Tags: EDITORIAL Source Type: research
Crohn ’s disease is a type of inflammatory bowel disease. There is no single test for diagnosing it. A doctor might order a few different tests to confirm a diagnosis. Here, learn how doctors test for and diagnose Crohn’s disease.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Crohn's / IBD Source Type: news
CONCLUSIONS: the prevalence of CeD in our patients with IBD was higher than that reported in the literature for other series of patients with IBD. A combination of anti-tTG testing and CeD genetics may screen patients for CeD in this population of patients with IBD. PMID: 31718200 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
CONCLUSION: Patients showed a good response to a seton procedure combined with IFX therapy regardless of the time of initiation of IFX therapy. PMID: 31726000 [PubMed]
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
Authors: Lee JL PMID: 31725995 [PubMed]
Source: Annals of Coloproctology - Category: Gastroenterology Tags: Ann Coloproctol Source Type: research
Condition:   Crohn Disease Interventions:   Drug: 5-aminolevulinic acid;   Procedure: Blue light photopheresis;   Procedure: Transfusion;   Procedure: Continuous Mononuclear Cell Collection (CMNC) Sponsors:   University Hospital, Akershus;   Oslo University Hospital Not yet recruiting
Source: - Category: Research Source Type: clinical trials
CONCLUSIONS: The requirement for proctectomy after hemorrhoidectomy/skin tag excision appears to be secondary to the natural disease course of perianal Crohn’s disease rather than perianal intervention. Selective hemorrhoidectomy and skin tag excision in patients with well-controlled luminal disease should be considered. See Video Abstract at HEMORROIDECTOMÍA ASOCIADA A LA EXCISIÓN DE PLICOMAS EN CASOS DE ENFERMEDAD INFLAMATORIA INTESTINAL: ¿ANUNCIO DE FATALIDAD O SIMPLEMENTE EVOLUCIÓN NATURAL DE LA ENFERMEDAD? ANTECEDENTES: Está controvertida la ...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Inflammatory Bowel Disease Source Type: research
ConclusionsStapled functional end-to-end ileocolic anastomosis is associated with fewer leaks than handsewn anastomosis.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research
Abstract OBJECTIVE: To explore the potential roles of Dickkopf-1 (DKK-1) and b-catenin in Crohn disease, and to evaluate the effects of a tumor necrosis factor (TNF)-a inhibitor on Wnt signaling in patients with the disease. METHODS: We enrolled 21 patients who received infliximab treatment for one year and achieved clinical remission during the treatment period. Disease activity was graded according to the Pediatric Crohn's Disease Activity Index (PCDAI). Peripheral blood and colonic mucosal specimens were collected from all patients with Crohn disease and from 14 healthy controls. DKK-1 levels in serum were...
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
Authors: Khorshidi M, Djafarian K, Aghayei E, Shab-Bidar S Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disorder which affects the gastrointestinal tract. Many factors, such as genetics, stress, and dietary patterns have been related to the risk of this disease. Adherence to a prudent/healthy dietary pattern, due to its antioxidant and anti-inflammatory properties, help to reduce the risk of many chronic diseases such as IBD. The results from previous studies regarding the association between dietary patterns and risk of IBD, including Crohn's disease (CD) and ulcerative colitis (UC), are in...
Source: International Journal for Vitamin and Nutrition Research - Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research
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