Hepatic Vascular Tumors in the Neonate: Angiosarcoma

A 6-week-old infant girl presented to a local emergency department with blood-tinged emesis, lethargy, decreased oral intake, abdominal distension, and a pale appearance. Pregnancy was uncomplicated except for preterm labor with spontaneous vaginal delivery at 36 weeks' gestation. Initial laboratory values were significant for severe anemia (hemoglobin of 4.9  g/dL and hematocrit of 15.9%), thrombocytopenia (platelets of 61 000), and mild coagulopathy (prothrombin time of 17.8 seconds, international normalized ratio of 1.62, and partial thromboplastin time was 21.3); asparate aminotransferase level was 218 IU/L, alanine aminotransferase 19 IU/L, and glutamyl transferase 723 IU/L.

Source: The Journal of Pediatrics - November 30, 2017 Category: Pediatrics Authors: Courtney Kiser McLean, Judy H. Squires, Miguel Reyes-M úgica, Andrew McCormick, Burhan Mahmood Tags: Grandrounds Source Type: research