Granular cell basal cell carcinoma: a case report

We report the case of a 47‐year‐old man who presented with an ulceration on his right upper lip which was subsequently removed. Histopathologic examination revealed that the tumor was composed solely of granular cells with numerous cytoplasmic eosinophilic round inclusion bodies. Mitotic figures ranged from 8 to 15 per 10 high‐power fields with a Ki‐67 proliferative index approximated at 5%. Immunohistochemically, the granular cells showed strong and diffuse positivity for Ber‐EP4, pan‐cytokeratin, AE1/AE3, CK5/6, and p63 and focal positivity for lysozymes, CD68 (clone KP1) and Bcl‐2.

Source: Journal of Cutaneous Pathology - November 28, 2017 Category: Pathology Authors: Xinyi Ma, Guihua Wang, Aditya Kuwadekar, Min Zhao, Weili Hu, Yeqin Wu, Zhongliang Yi, Xianen Xu, Li Xu Tags: CASE REPORT Source Type: research