Interleukin-37 Relieves Allergic Inflammation in a House Dust Mite Allergic Rhinitis Murine Model.

This study demonstrates that intranasal IL-37 can suppress Th2 and Th17 responses in an AR murine model. Furthermore, these data suggest that IL-10 is increased, but CD4+CD25+Foxp3+T cells are not correlated with the IL-37-induced mechanism.
PMID: 29149780 [PubMed - in process]

Source: Iranian Journal of Allergy, Asthma and Immunology - October 1, 2017 Category: Allergy & Immunology Authors: Kim DH, Kim SW, Kim SW, Kang JM Tags: Iran J Allergy Asthma Immunol Source Type: research