One in Three Cases of Alzheimer’s May be Lifestyle Related

Scientists who attended the 2014 Alzheimer's Association International Conference in Copenhagen this month seem energized from their collaborative effort. News stories will be filtering out for weeks to come about the studies presented at the conference. However, to me, one of the most interesting and encouraging conclusions so far is that lifestyle changes may hold back Alzheimer’s symptoms for up to 10 years.   Over the last decade,...
Source: Carol Bradley Bursack's SharePosts - Category: Dementia Authors: Source Type: blogs

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Commentary on "When and How to Treat Agitation in Alzheimer's Disease Dementia With Citalopram and Escitalopram". Am J Geriatr Psychiatry. 2019 May 27;: Authors: Pollock BG PMID: 31208921 [PubMed - as supplied by publisher]
Source: The American Journal of Geriatric Psychiatry - Category: Psychiatry Tags: Am J Geriatr Psychiatry Source Type: research
CONCLUSIONS: Longitudinal analysis of correctly scaled neuropsychological assessments may provide unbiased proxies for MRI-based measures of dementia risk. PMID: 31206372 [PubMed - as supplied by publisher]
Source: Alzheimer Disease and Associated Disorders - Category: Psychiatry Tags: Alzheimer Dis Assoc Disord Source Type: research
Cerebral amyloid angiopathy (CAA) consists of beta-amyloid deposition in the walls of the cerebrovasculature and is commonly associated with Alzheimer's disease (AD). However, the association of CAA with repetitive head impacts (RHI) and with chronic traum...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Discussion and conclusionNon-linear registration methods were most consistent in determining hippocampal atrophy and because of their better reproducibility, methods, such as ANTs, Elastix and NiftyReg, are preferred for determining hippocampal atrophy rates on longitudinal MRI. Since performances of non-linear registration methods are well comparable, the preferred method would mostly depend on computational efficiency.
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Condition:   Alzheimer Disease Interventions:   Drug: Montelukast;   Drug: Placebo oral tablet Sponsor:   Emory University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Alzheimer Disease Interventions:   Diagnostic Test: cognitive assessment;   Other: Inhibition evaluation;   Other: Assessment of mental flexibility;   Other: Evaluation of the update;   Other: working memory;   Other: episodic memory Sponsor:   Centre Hospitalier Universitaire de Saint Etienne Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 19 June 2019Source: Alzheimer's &DementiaAuthor(s): George A. Mashour, Lori Frank, Alexander Batthyany, Ann Marie Kolanowski, Michael Nahm, Dena Schulman-Green, Bruce Greyson, Serguei Pakhomov, Jason Karlawish, Raj C. ShahAbstractUnexpected cognitive lucidity and communication in patients with severe dementias, especially around the time of death, have been observed and reported anecdotally. Here, we review what is known about this phenomenon, related phenomena that provide insight into potential mechanisms, ethical implications, and methodologic considerations for systematic investig...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
An in-depth look at violence and its relation to schizophrenia. Is violence a symptom of schizophrenia? Do mass attackers always have schizophrenia? Are schizophrenics dangerous? Studies say people with schizophrenia are more likely to be a victim of a crime than the perpetrator. However, James Holmes, the movie theater mass murderer, was said to have paranoid schizophrenia. And a person can plead not-guilty by reason of insanity in court. This seems to be contrary to the idea of non-violence in mental illness. Host Rachel Star Withers, a diagnosed schizophrenic, and co-host Gabe Howard delve into these intense subjects i...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Inside Schizophrenia Stigma Violence and Aggression Mental Disorder Mental Health Mental Illness Paranoid Schizophrenia violence and mental illness violence and mentally ill Source Type: blogs
Contributors : Ignazio S Piras ; Jonida Krate ; Elaine Delvaux ; Jennifer Nolz ; Diego F Mastroeni ; Antonio M Persico ; Wayne M Jepsen ; Thomas G Beach ; Matthew J Huentelman ; Paul D ColemanSeries Type : Expression profiling by arrayOrganism : Homo sapiensWe used Illumina Human HT-12 v4 arrays to compare RNA expression of middle temporal gyrus (MTG; BA21) in Alzheimer ’s Disease (AD = 97) and non-demented controls (ND = 98). A total of 938 transcripts were highly differentially expressed (adj p
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research
ACS Chemical BiologyDOI: 10.1021/acschembio.9b00309
Source: ACS Chemical Biology - Category: Chemistry Authors: Source Type: research
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