Treatment with Ziprasidone for schizophrenia patients with OCD

Comorbidity of obsessive–compulsive disorder (OCD) has been observed in about 15% of schizophrenic patients and has been associated with poor prognosis. Therefore, there is a need for specific treatment options for these patients (schizo-obsessive, ScOCD).This is an open, prospective study, aiming to test the efficacy of Ziprasidone (80–200mg/d) in ScOCD patients and comparing the response to the treatment between stable schizophrenic (N=16) and stable ScOCD (N=29) patients.Treatment effect with Ziprasidone was different in schizophrenic patients when stratified based on OCD comorbidity.

Source: European Neuropsychopharmacology - July 3, 2014 Category: Psychiatry & Psychology Authors: Alzbeta Juven-Wetzler, Leah Fostick, Shlomit Cwikel-Hamzany, Evgenya Balaban, Joseph Zohar Source Type: research