Allergy to oxidized limonene and linalool is frequent in the U.K.

ConclusionsThis large, multicentre U.K. audit shows a significant rate of allergy to the hydroperoxides of limonene and linalool plus a high rate of irritant reactions. Testing to the oxidized forms alone captures the majority (97·0%; 411 of 422) of positive reactions; testing to nonoxidized terpenes appears to be less useful. We recommend that the hydroperoxides of limonene and linalool be added to an extended baseline patch test series.

Source: British Journal of Dermatology - July 26, 2014 Category: Dermatology Authors: H. Audrain, C. Kenward, C.R. Lovell, C. Green, A.D. Ormerod, J. Sansom, M.M.U. Chowdhury, S.M. Cooper, G.A. Johnston, M. Wilkinson, C. King, N. Stone, H.L. Horne, C.R. Holden, S. Wakelin, D.A. Buckley Tags: Cutaneous Allergy Source Type: research