[Correspondence] Hospital antimicrobial stewardship: the way forward – Authors' reply

Discussion section, we completely agree that the possibility of uncontrolled studies having observed effects as a result of an underlying secular trend cannot be ignored, and we also recommended the use of controll ed interventional designs for future studies. However, we would like to underline that, although some guidance is available on how to design interventions on antimicrobial stewardship,2 specific recommendations about how to select study designs and overcome major bias in assessing antibiotic steward ship programmes (eg, definitions of outcomes or analytical methods) are missing or under development.
Source: The Lancet Infectious Diseases - Category: Infectious Diseases Authors: Tags: Correspondence Source Type: research