Parametric Linkage Analysis Identifies Five Novel Genome-Wide Significant Loci for Familial Lung Cancer

Conclusions: The 5 novel signals are good candidate regions, containing genes that have been implicated as having somatic changes in lung cancer or other cancers (though not in germ line cells). Targeted sequencing on the significant loci is planned to determine the causal variants at these loci.Hum Hered 2016;82:64-74

https://www.karger.com/Article/FullText/479028

Source: Human Heredity - October 25, 2017 Category: Genetics & Stem Cells Source Type: research