Homeostatic Γδ T-Cell Contents are Preserved by Granulocyte Colony-Stimulating Factor Priming and Correlate with the Early Recovery of Γδ T Subsets after Haploidentical Hematopoietic Transplantation

• The proportions of γδT subsets were preserved in PB grafts after G-CSF priming.• The abundant IFN-γ-production capacity of γδT was maintained post-mobilization.• Homeostatic donor γδT content correlated with the early γδT recovery after HSCT.• Day-30 Vδ1 recovery inversely correl ated with CMV reactivation in HSCT recipients.

Source: Biology of Blood and Marrow Transplantation - October 20, 2017 Category: Hematology Authors: Zhilei Bian, Lan-Ping Xu, Qiang Fu, Mingrui Huo, Long Liu, Xiaosu Zhao, Xiao-Jun Huang, Jiangying Liu Source Type: research