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Investigating Human Dendritic Cell Immune Responses to Borrelia burgdorferi.

Investigating Human Dendritic Cell Immune Responses to Borrelia burgdorferi. Methods Mol Biol. 2018;1690:291-299 Authors: Mason LMK, Hovius JWR Abstract Dendritic cells (DCs) are professional antigen-presenting cells that recognize and phagocytose pathogens, and help to orchestrate adaptive immune responses to combat them. DCs are abundant in the skin where Borrelia burgdorferi first enters the body during a tick bite, and are thus critical in determining the initial stages of the innate and adaptive immune responses against Borrelia. Here, we describe two methods to study the response of DCs to Borrelia; an in vitro approach using monocyte-derived DCs (moDCs) and an ex vivo approach using a human skin model. PMID: 29032552 [PubMed - in process]
Source: Mol Biol Cell - Category: Molecular Biology Authors: Tags: Methods Mol Biol Source Type: research

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Source: Medical Hypotheses - Category: Biomedical Science Authors: Source Type: research
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Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
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Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
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