Plasminogen Activator Inhibitor-1 Regulates the Vascular Expression of Vitronectin.

CONCLUSIONS: PAI-1 stimulates SMC VN expression by binding LRP1 and controls vascular VN expression in vivo. Autocrine regulation of vascular VN expression by PAI-1 may play important roles in vascular homeostasis and pathological vascular remodeling. This article is protected by copyright. All rights reserved.
PMID: 29028290 [PubMed - as supplied by publisher]

Source: Thrombosis and Haemostasis - October 13, 2017 Category: Hematology Authors: Luo M, Ji Y, Luo Y, Li R, Fay WP, Wu J Tags: J Thromb Haemost Source Type: research