Construction of Tetrahydropyranoquinoline Derivatives via an Asymmetric Organocatalytic aza-Michael-IED/HAD Cascade Reaction

Org. Biomol. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7OB02231J, PaperLu Dai, Yuxuan Hou, Lvye Zhang, Zhangtao Chen, Xiaofei Zeng, Guofu Zhong Chiral functionalized tetrahydroquinolines and pyranoquinolines with multiple stereogenic centres have emerged as attractive structures for derivatizing bioactive complex molecules. Herein, we developed a novel, facile organocatalytic asymmetric aza-Michael-IED/HAD cascade reaction... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Organic and Biomolecular Chemistry - October 12, 2017 Category: Molecular Biology Authors: Lu Dai Source Type: research