When potion becomes poison! A case report of flecainide toxicity

We report a 48-day-old female infant, who developed cardiac conduction abnormalities and seizures secondary to supratherapeutic doses of oral flecainide. Flecainide was started in this infant for treatment of supraventricular tachycardia. The drug was withdrawn with successful normalization of the QRS complex and no further recurrence of seizures. The Naranjo probability score for adverse drug reaction was 8, making the causality “probable.” The case restates an important message that physicians should be aware of the side effects of the drugs that they prescribe, especially of those drugs which have a narrow therapeutic window.
Source: Journal of Postgraduate Medicine - Category: Internal Medicine Authors: Source Type: research

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(Natural News) Scientists warn that cadmium poisoning is an underreported and little-known global health problem, causing a massive number of deaths annually and contributing to a lot of illnesses, not the least of which is cancer. The long-term exposure to the heavy metal has been documented to dramatically increase one’s risk of various skeletal, reproductive,...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
(Natural News) The next time you reach for that fresh-looking apple on the shelf of your grocer, you should reconsider taking a bite out of it lest you poison yourself. An article in Natural Health 365 warned that a nasty chemical covers four out of every five apples that were grown through conventional, non-organic means....
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
The objective of this study is to evaluate the risk of myocardial infarction following COP. Using a nationwide database of insurance claims in Taiwan, we conducted a population-based cohort study to identify COP patients diagnosed between 1999 and 2012. At a ratio of 3:1, we identified non-COP patients who were matched by the index date and age and compared the risk of myocardial infarction between the two cohorts by time after the index dates of the COP patients, until 2013. We identified 22,258 COP patients and 66,774 non-COP patients. COP patients had an increased risk of myocardial infarction, with an incidence rate ra...
Source: Cardiovascular Toxicology - Category: Cardiology Authors: Tags: Cardiovasc Toxicol Source Type: research
OBJECTIVE: To establish the indexes and weights of risk assessment of shellfish poisoning outbreak caused by red tide. METHODS: The risk assessment indexes were developed with the methods of literature review, brainstorm and expert consultation, an...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
The experimental pathophysiology of organophosphorus (OP) chemical exposure has been extensively reported. Here, we describe an altered fecal bacterial biota and urine metabolome that follows intoxication with soman, a lipophilic G class chemical warfare n...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Poisoning Source Type: news
(Reuters Health) - Homeowners in North Carolina and South Carolina who lost electricity in the wake of Hurricane Florence need to realize that backup generators and other temporary power sources can cause carbon monoxide poisoning, scientists warn.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
The renowned science writer joined our podcast to discuss the chemist and experiment behind the ‘The Poison Squad.’
Source: Chemical and Engineering News - Category: Chemistry Authors: Source Type: research
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Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Infectious Diseases News Source Type: news
Publication date: December 2018Source: Harmful Algae, Volume 80Author(s): Urban Tillmann, Bente Edvardsen, Bernd Krock, Kirsty F. Smith, Ruth F. Paterson, Daniela VoßAbstractAzaspiracids (AZA) are a group of lipophilic polyether compounds which have been implicated in shellfish poisoning incidents around Europe. They are produced by a few species of the dinophycean genera Azadinium and Amphidoma (Amphidomataceae). The presence of AZA toxins in Norway is well documented, but knowledge of the distribution and diversity of Azadinium and other Amphidomataceae along the Norwegian coast is rather limited and poorly documen...
Source: Harmful Algae - Category: Environmental Health Source Type: research
Resumo Propor uma lista-refer ência de códigos da Classificação Internacional de Doenças e Problemas Relacionados à Saúde (CID-10) para a vigilância de reações adversas e intoxicações a medicamentos, denominados de eventos adversos. A elaboração da lista-referência percorreu quatro fases: definição dos códigos, validação e duas de caracterização da lista. As associações entre variáveis foram avaliadas por qui-quadrado de Pearson e análise de corre...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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