Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina

AbstractTwo new gallic acid glycosides, potentillanosides G (1) and H (2), were newly isolated from the methanol extract of the tuberous roots ofPotentilla anserina (Rosaceae), together with a known compound, ellagic acid 3-O- α-l-rhamnopyranoside (3). Their structures were elucidated on the basis of chemical and physicochemical evidence. Among the constituents, potentillanoside H (2, IC50 = 99.5 μM) was found to show hepatoprotective activity.
Source: Journal of Natural Medicines - Category: Drugs & Pharmacology Source Type: research