Statins vs. Niacin

Title: Statins vs. NiacinCategory: MedicationsCreated: 10/6/2017 12:00:00 AMLast Editorial Review: 10/6/2017 12:00:00 AM
Source: MedicineNet Cholesterol General - Category: Cardiology Source Type: news

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Statins are now the most commonly used drug in the UK and one of the most commonly used medicines in the world, but debate remains about their use for primary prevention for people without cardiovascular disease. Paula Byrne from the National University of Ireland Galway, joins us to talk about the evidence of benefit for low risk individuals,...
Source: The BMJ Podcast - Category: General Medicine Authors: Source Type: podcasts
The objective of this study was to report on long-term survival of major lower limb amputees after rehabilitation as well as to identify factors leading to poorer survival.
Source: Journal of Vascular Surgery - Category: Surgery Authors: Source Type: research
Authors: Iqbal Z, Dhage S, Mohamad JB, Abdel-Razik A, Donn R, Malik R, Ho JH, Liu Y, Adam S, Isa B, Stefanutti C, Soran H Abstract Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are novel drugs that have been developed since the discovery of the PCSK9 protein in 2003. In addition to background statin treatment they reduce low density lipoprotein cholesterol (LDL-C) to unprecedented levels and have shown encouraging results in improving cardiovascular events. Concerns regarding the safety of PCSK9 inhibitors and very low LDL-C have somewhat been allayed after several longer-term prosp...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
In conclusion, this preliminary pharmacogenetic study identifies thatCOQ2 gene polymorphism (rs4693075, G  >  C), notTNF- α gene polymorphism (rs1799724, C  >  T), is involved in causing statin-induced myopathy in Bangladeshi hyperlipidemic patients.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 18 October 2019Source: Canadian Journal of CardiologyAuthor(s): Dirk G. Struijk
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Atrial fibrillation (AF) is a common cause of cerebral infarction, which could lead to endothelial dysfunction, increased reactive oxygen species (ROS) and oxidized low density lipoprotein (Ox-LDL).AF is assoc...
Source: BMC Neurology - Category: Neurology Authors: Tags: Research article Source Type: research
Background and aims: Atrial fibrillation (AF) is a major cause of ischemic stroke; however, detailed clinical data and prognostic factors for stroke patients with AF are lacking in Korea. We aimed to investigate clinical information and factors associated with functional outcomes of stroke patients with AF from the Korean nationwide ATrial fibrillaTion EvaluatioN regisTry in Ischemic strOke patieNts (K-ATTENTION) database.Methods: From January 2013 to December 2015, consecutive clinical information from acute stroke patients with AF or history of AF was collected from 11 centers in Korea. Collected data included demographi...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Abstract NMR measurements of 19F chemical shift anisotropy and 1H-19F dipolar couplings provide unprecedented information on the molecular orientations of two fluorine-containing statin drugs within the heterogeneous environment of reconstituted high-density lipoprotein (rHDL) nanoparticles, a drug delivery system under clinical investigation. PMID: 31626247 [PubMed - as supplied by publisher]
Source: Chemical Communications - Category: Chemistry Authors: Tags: Chem Commun (Camb) Source Type: research
Changes in clinical guidelines have increased the number of people eligible to take statins. In many countries, the majority of people taking the drugs do so for primary prevention.
Source: WebMD Health - Category: Consumer Health News Source Type: news
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