P2Y1R is involved in visceral hypersensitivity in rats with experimental irritable bowel syndrome.

CONCLUSION: P2Y1R plays a regulatory role in visceral hypersensitivity in rats with experimental IBS. Specific antagonists of P2Y1R may have potential therapeutic value in treating abdominal pain in IBS.
PMID: 28974901 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - September 14, 2017 Category: Gastroenterology Authors: Wu J, Cheng Y, Zhang R, Liu D, Luo YM, Chen KL, Ren S, Zhang J Tags: World J Gastroenterol Source Type: research