Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B cell function and inhibition of the PD-1/PD-L1 pathway

Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B cell function and inhibition of the PD-1/PD-L1 pathwayLeukemia, Published online: 3 October 2017; doi:10.1038/leu.2017.304

Source: Leukemia - October 3, 2017 Category: Hematology Authors: K Kondo H Shaim P A Thompson J A Burger M Keating Z Estrov D Harris E Kim A Ferrajoli M Daher R Basar M Muftuoglu N Imahashi A Alsuliman C Sobieski E Gokdemir W Wierda N Jain E Liu E J Shpall K Rezvani Source Type: research