Changes in inflammatory mediators as a result of intermittent hypoxia in obstructive sleep apnea syndrome

Conclusions: PTX‐3 can be a new indicator reflecting the inflammatory state in patients with OSAS. Since patients with OSAS could have more hypoxic state during sleep, we found higher PTX‐3 level in those patients and a negtive corralation between PTX‐3 and minimum SaO2, which could explain that PTX‐3 levels can increase with the severity of disease. Our results suggest that PTX‐3 as an inflammatory biomarker may play a crucial role as an indicator of syndrome severity in OSAS. This article is protected by copyright. All rights reserved.

Source: The Clinical Respiratory Journal - September 1, 2017 Category: Respiratory Medicine Authors: Volkan Sozer, M üge Kutnu, Ersan Atahan, Buket Calıskaner Ozturk, Ergi Hysi, Cansu Cabuk, Benan Musellim, Gonul Simsek, Hafize Uzun Tags: Original Article Source Type: research