Cardiovascular PET/MRI: Technical Considerations and Outlook

AbstractPurpose of ReviewWe aim to provide insights into current and future applications of cardiac PET/MRI and the logistical issues one should consider when implementing a program using this still novel technology.Recent FindingsSince their introduction around 15  years ago, PET/CT and SPECT/CT hybrid imaging devices saw high clinical utilization, which was driven clearly by oncology. Fortunately, the basic availability in a clinical setting enabled the investigation of the cardiac imaging perspective and facilitated numerous research activities. Given the fact that cardiac MRI is a very attractive research field with an increasing clinical utilization, PET/MRI raised the expectation of innovative imaging scenarios with synergistic applications. Integrating molecular imaging with a multitude of PET agents and the high temporal and spatial resolution o f MRI are ideally suited for novel applications having especially a reduced burden of ionizing radiation and potentially a lack of contrast media in mind.SummaryThe technical complexity and consequentially the considerable amount of monetary investment resulted until today in a limited availability and experience. However, the potential of these systems are currently unsurpassed as they really implement a “best of both worlds” approach.
Source: Current Cardiovascular Imaging Reports - Category: Radiology Source Type: research

Related Links:

Conclusions: 99mTc-MIBI SPECT/CT can increase the sensitivity and consistency of preoperative localization of eutopic parathyroid glands, and it can accurately locate ectopic parathyroid without sensitivity improvement. PMID: 31537128 [PubMed - in process]
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Authors: Wei L, Osman S, Hatt M, El Naqa I Abstract Due to the recent developments of both hardware and software technologies, multimodality medical imaging techniques have been increasingly applied in clinical practice and research studies. Previously, the application of multimodality imaging in oncology has been mainly related to combining anatomical and functional imaging to improve diagnostic specificity and/or target definition, such as positron emission tomography/computed tomography (PET/CT) and single-photon emission computed tomography (SPECT)/CT. More recently, the fusion of various images, such as multi-...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
Polypeptide ‐based nanoagents featuring high iodine content, fascinating physicochemical properties, great simplicity, good safety, and remarkable potency, hold a tremendous potential in both diagnosis and therapy of varying diseases. AbstractFuture healthcare requires development of novel theranostic agents that are capable of not only enhancing diagnosis and monitoring therapeutic responses but also augmenting therapeutic outcomes. Here, a versatile and stable nanoagent is reported based on poly(ethylene glycol) ‐b‐poly(l‐thyroxine) (PEG‐PThy) block copolypeptide for enhanced single photon emission computed tom...
Source: Small - Category: Nanotechnology Authors: Tags: Full Paper Source Type: research
ConclusionQuantitative99mTc-DPD SPECT/CT in suspected ATTR CA patients is feasible and allows for a more accurate assessment of myocardial uptake.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
AbstractWe aimed to investigate whether the frontal lobe bottom and cerebellum tuber vermis (FLB –CTV) line on brain perfusion scintigraphy, using iodine-123 isopropyl iodoamphetamine single photon emission computed tomography (I-123 IMP SPECT) images, is useful to determine an axial angle parallel to the anterior commissure-posterior commissure (AC–PC) line. We measured the angular differe nces between the AC–PC line and the FLB–CTV line on midsagittal brain magnetic resonance imaging (MRI) scans of 100 patients. We also evaluated the angular differences of the FLB–CTV line between the IMP SP...
Source: Radiological Physics and Technology - Category: Physics Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Condition:   Dimercaptosuccinic Acid SPECT and Planar Intervention:   Device: Gamma camera imaging Sponsor:   Assiut University Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Publication date: Available online 13 September 2019Source: Life SciencesAuthor(s): Sajjad Ahmadpour, Seyed Jalal HosseinimehrAbstractBreast cancer deaths occur mainly because of poor diagnosis in early stages that lead to tumor metastasis in advanced stages. Developing a high-sensitive early-stage breast cancer diagnostic tool based on single photon emission computer tomography (SPECT) and positron emission tomography (PET) are urgent. There are several evidences to demonstrate the prominent roles of specific receptors overexpression in tumor initiation and progression of breast cancer. Targeting of specific receptor with...
Source: Life Sciences - Category: Biology Source Type: research
Conclusion We found that normal values of phase analysis can vary among software programs and can be different even when the same software is used.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Review Article Source Type: research
Conclusion The results of this survey suggest that the future of truly quantitative SPECT looks promising.
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research
More News: Cancer & Oncology | Cardiology | Cardiovascular | Heart | Radiology | SPECT