Fasting Spot-urine pH is Associated with Metabolic Syndrome in the Japanese Population

Objective: To investigate the relationship between urine pH and metabolic syndrome (MetS) and its components while controlling for covariates. Subjects and Methods: This cross-sectional study was conducted on 5,430 Japanese subjects (4691 without MetS; 739 with MetS) undergoing health assessments. Partial correlation analysis and analysis of covariance were used for controlling confounding parameters (age, gender, serum uric acid (UA) levels, high sensitivity C-reactive protein, estimated glomerular filtration rate, and smoking and drinking statuses). Using multiple logistic regression analyses, adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for MetS incidence were calculated across urine pH categories. Path analysis was used to determine the relationship between MetS and urine pH. Results: Subjects with MetS had significantly lower urine pH (5.9 ± 0.7) than those without MetS (6.0 ± 0.7) (p
Source: Medical Principles and Practice - Category: Internal Medicine Source Type: research