Cholesterol-like molecules switch off the engine in cancer-targeting Natural Killer cells

(Trinity College Dublin) The engine used by cancer-killing 'Natural Killer' cells is turned on by a protein called Srebp, which can be blocked by certain sterols like cholesterol. Tumor cells can produce oxysterols and cholesterol levels tend to be higher in people with obesity.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news