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Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news

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Thu, 06/21/2018 - 16:05News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Chitin is a polysaccharide that provides structure and rigidity to the cell walls of fungi and insects. Mammals possess multiple chitinases, which function to degrade chitin, thereby supporting a role for chitinases in immune defense. However, chitin degradation has been implicated in the pathogenesis of asthma. Here, we determined the impact of acidic mammalian chitinase (AMCase) (Chia) deficiency on host defense during acute exposure to the fungal pathogen Aspergillus fumigatus as well as its contribution to A. fumigatus-associated allergic asthma. We demonstrate that chitin in the fungal cell wall was detected at low le...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Host Response and Inflammation Source Type: research
Publication date: October 2018 Source:Steroids, Volume 138 Author(s): Ahmed S. Abdel-Razek, Abdelaaty Hamed, Marcel Frese, Norbert Sewald, Mohamed Shaaban Penicisteroid C, a new polyoxygenated steroid was isolated from co-cultivation of Streptomyces piomogenus AS63D and Aspergillus niger using solid-state fermentation on rice medium. Additional diverse eleven known metabolites were identified: Fumigaclavine C, fumiquinazoline C, physcion, methylsulochrin, methyllinoleate, glycerol linoleate, cerebroside A, thymine, adenine, thymidine and adenosine. The structure of penicisteroid C was determined by HRESIMS, 1D and 2D NMR ...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
Publication date: August 2018 Source:Steroids, Volume 136 Author(s): Yu Chen, Yi Dong, Yuanlong Chi, Qiang He, Hui Wu, Yao Ren A novel microbial procedure was proposed for diosgenin production from Dioscorea zingiberensis C.H. Wright (DZW) tubers via employing Aspergillus awamori for the first time. The optimal conditions of fermenter cultivation were established as inoculation dosage of 8%, fermentation temperature of 30 °C, cultivation time of 8 days, initial pH of 7.0 and a stirring rate of 180 rpm when the converted diosgenin content reached a peak value of 74.26 ± 3.23 mg/g substrate. The produ...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
The pulmonary mucus of cystic fibrosis (CF) patients displays elevated levels of the cathelicidin antimicrobial peptide LL-37, and the aim of this work was to assess the effect of LL-37 on the growth of Aspergillus fumigatus, a common pathogen of CF patients. Exposure of A. fumigatus to LL-37 and its derived fragment RK-31 (1.95 μg/ml) for 24 h had a positive effect on growth (199.94% ± 6.172% [P
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Fungal and Parasitic Infections Source Type: research
2018Post date: Wednesday, June 20, 2018 - 17:39Books and theses
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Wed, 06/20/2018 - 08:13News blog
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Authors: Dutta D, Debnath DAS M Abstract  In present study, Taguchi's design of experiment L9 orthogonal array was created using Qualitek-4 software with four most critical factors namely, K2HPO4, MgSO4, CaCl2 and culture pH. Production of a new intracellular antifungal protein in submerged fermentation was optimized with yield of 0.98±0.1 mg/gram dry cell weight mycelia from Aspergillus giganteus MTCC 8408. The average molecular mass of the purified protein was figured as 5.122 kDa using Electro Spray Ionization-Mass Spectrometry. Scanning electron microscopy was used to correlate the effect of selected f...
Source: Biocontrol Science - Category: Microbiology Tags: Biocontrol Sci Source Type: research
Cellular Microbiology, EarlyView.
Source: Cellular Microbiology - Category: Microbiology Authors: Source Type: research
Publication date: 30 November 2018 Source:Food Chemistry, Volume 267 Author(s): Eva M. Mateo, José Vicente Gómez, Noemí Montoya, Rufino Mateo-Castro, José Vicente Gimeno-Adelantado, Misericordia Jiménez, Antonio Doménech-Carbó An electrochemical methodology for the characterization of mycotoxin-producing fungal species from the genera Aspergillus and Fusarium using solid-state voltammetry is described. Upon attachment of fungal colony microsamples to glassy carbon electrodes in contact with aqueous acetate buffer, characteristic voltammetric signals mainly associated to the...
Source: Food Chemistry - Category: Food Science Source Type: research
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