U.S. senator reveals results of opioid inquiry into Insys

BOSTON (Reuters) - Insys Therapeutics Inc sought to manipulate the process to gain insurance payment approval for an opioid cancer pain drug called Subsys even if for inappropriate uses, according to a U.S. Senate report related to the national opioid addiction crisis released on Wednesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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AbstractOpioid overdose accounted for more than 47,000 deaths in the United States in 2018. The risk of new persistent opioid use following breast cancer surgery is significant, with up to 10% of patients continuing to fill opioid prescriptions one year after surgery. Over prescription of opioids is far too common. A recent study suggested that up to 80% of patients receiving a prescription for opioids post-operatively do not need them (either do not fill the prescription or do not use the medication). In order to address this important issue, The American Society of Breast Surgeons empaneled an inter-disciplinary committe...
Source: Annals of Surgical Oncology - Category: Cancer & Oncology Source Type: research
Digital media&downloads Pain Relief Caused by SARS-CoV-2 Infection May Help Explain COVID-19 Spread New research shows SARS-CoV-2 promotes pain relief when it infects cells through a common protein receptor, neuropilin-1. The finding gives scientists a novel target for non-opioid pain therapeutics, while also offering an explanation for the unrelenting spread of COVID-19. Stacy Pigott Today University of Arizona Health SciencesKhanna_Raj_klh3067.jpg Doctoral student Lisa Boinon prepares buffers while Rajesh Khanna looks on. (Photo: Kris Hanning/University of Arizona Health Sciences)HealthCollege of Medicine - Tuc...
Source: The University of Arizona: Health - Category: Universities & Medical Training Authors: Source Type: research
Some existing therapies for treatment of pain are administered systematically and have significant side effects, such as addiction and drowsiness. Alternative therapy that does not impair normal touch function could be used to treat pain caused by mechanical injury or chronic inflammation. Administration of margaric acid was shown to ameliorate pain in mouse models of pain. In vitro data shows that margaric acid counteracts PIEZO2 (Piezo-type mechanosensitive ion channel component 2) potentiation evoked by bradykinin (i.e. a peptide that promotes inflammation) by reducing the mechanocurrents up to non-inflammatory levels. ...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
Having trouble viewing this email? View it as a Web page. NIDCR's Fall 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News NIDCR Announces Availability of COVID-19 Research Funding On May 5, NIDCR issued two Notices of Special Interest highlighting the urgent need for research on coronavirus disease 2019. This research may be conducted either via the National Dental PBRN infrastructu...
Source: NIDCR Science News - Category: Dentistry Source Type: news
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
(Arizona State University) A team of scientists from ASU's School of Molecular Sciences and the Biodesign Institute have recently published a study in Nature Communications that helps clarify the contributions to an ion channel's temperature - dependent activation. This in turn should aid in the development of new types of non-addictive pain therapies.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Authors: Amezcua V, Doello K, González-Callejas D PMID: 32819770 [PubMed - as supplied by publisher]
Source: Medicina Clinica - Category: General Medicine Tags: Med Clin (Barc) Source Type: research
This article idea was suggested by a Conscious Growth Club member. After a little reflection, I thought, why not? I’ve seen every episode of every non-animated Star Trek series, including the original 1960s classic, The Next Generation, Deep Space Nine, Voyager, Enterprise, Discovery, and the new Picard series. I’ve seen many episodes multiple times. I’ve seen all of the movies. I’ve been to a Star Trek Convention in Las Vegas. So I’m pretty well versed in Star Trek lore. I met William Shatner (aka Captain Kirk) very briefly when I was in my 20s because we had the same lawyer for a while...
Source: Steve Pavlina's Personal Development Blog - Category: Psychiatry & Psychology Authors: Tags: Lifestyle Values Source Type: blogs
Pausing to check his map, Sam confirms that he is on the right track for his next delivery, only 2 kilometres left. He takes the opportunity to quench his thirst and check if his delivery load is securely attached to his back; some contain fragile vials of medicines and digital pills susceptible to damage if handled inappropriately. After making sure of the integrity of those packages, Sam takes a final look at his surroundings. “It’s quite peaceful with nobody around,” he thinks to himself and resumes his path.  Upon arrival at his destination, his gear is disinfected before he has access to the ...
Source: The Medical Futurist - Category: Information Technology Authors: Tags: Artificial Intelligence Augmented Reality Digital Health Research Healthcare Design Healthcare Policy Telemedicine & Smartphones Virtual Reality fda gamification Fitbit covid19 Apple Watch WHO gaming roche MySugr Foldit A Source Type: blogs
“My step-father abused me, and my mother is always telling me to forgive and forget.” Jodie shook her head ruefully. “And how is that going for you?” I ask. “Not so good,” Jodie replies, “I’m not doing a good job at all.” Alex shares, “My counselor told me if I don’t forgive my uncle for raping me, then I’m allowing him to live rent-free in my head.” “And how is that going for you?” I ask. “Not so good,” Alex cries, “I feel like I’m failing at recovery!” Both Jodie and Alex — and countless other sur...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Abuse PTSD Trauma Violence and Aggression Anger Forgiveness Rape Resentment Sexual Abuse Sexual Assault Sexual Trauma Source Type: blogs
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