Duodenal nutrient exclusion improves metabolic syndrome and stimulates villus hyperplasia

Conclusions
Our preclinical results validate DES as a promising therapeutic approach to diabetes and obesity, which offers reversibility, low risk, low invasiveness and triple benefits including fat mass loss, glucose and lipid metabolism improvement which mechanistically may involve increased villus growth in the upper gut.

Source: Gut - July 8, 2014 Category: Gastroenterology Authors: Habegger, K. M., Al-Massadi, O., Heppner, K. M., Myronovych, A., Holland, J., Berger, J., Yi, C.-X., Gao, Y., Lehti, M., Ottaway, N., Amburgy, S., Raver, C., Muller, T. D., Pfluger, P. T., Kohli, R., Perez-Tilve, D., Seeley, R. J., Tschop, M. H. Tags: Small bowel Source Type: research