TSH oscillations in young patients with type 1 diabetes may be due to glycemic variability

ConclusionsOur results suggest a direct action of glycemic excursions on TSH secretion, regardless of variations of thyroid hormone concentrations. Thus, the evaluation of thyroid function through the assay of TSH concentrations in these patients should be made, if possible, by multiple samples on patients in euglycemic state to avoid underestimation or overestimation of thyroid dysfunction due to a wrong diagnosis of euthyroidism or dysthyroidism with consequent inappropriate choice of therapeutic options.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research